Table 2 Proposed functions of ORFs in the putative lasso peptide biosynthetic gene cluster identified by genome mining in Paenibacillus sp. PL91 and reported Bacillus Dendrifitormis C454
Gene | Paeninodin Paenibacillus dendritiformis C454 | Gene | Lasso peptide BGC Paenibacillus PL91 |
|---|---|---|---|
pade C | Maduration enzyme, cyclization, adenylation | 1 | Isopeptide bond cyclase |
padeA | Precursor peptide | 2 | Precursor peptide |
padeK | Putative kinase | 3 | Aldolase |
padeB1 | Maturation enzyme PqqD superfamily B1 part of “split B”, protease | 4 | Maturation enzyme PqqD chaperone |
padeB2 | Maturation enzyme, transglutaminase like superfamily B2 part of “split B”, protease | 5 | B2 protein maturation enzyme |
padeD | Export ABC type transport system | 6 | ABC transporter ATP-binding protein |