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Fig. 5 | BMC Genomics

Fig. 5

From: The cellular response to drug perturbation is limited: comparison of large-scale chemogenomic fitness signatures

Fig. 5

Compounds and mechanisms of action can be inferred by coinhibition with reference compounds. A The high coinhibition of the HIPLAB HIP amphotericin chemogenomic profile with two NIBR profiles (4247 and 1020) suggests all three compounds act by the same mechanism. B A series of four compounds, 1208, 1209, 1210 and 1211 (only 1208 and 1210 are shown) recapitulated the hydroxyurea chemogenomic profile nearly perfectly suggesting they might be structural analogs

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BMC Genomics

ISSN: 1471-2164

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