Fig. 2
The Aeromonas veronii genomic island AVI-1 containing the T3SS system. The AVI-1 genomic island identified in this study contains genes encoding T3SS, which is found in 106 of the 168 strains examined in this study. A The prevalence of T3SS in strains isolated from patients with gastrointestinal diseases was significantly lower than that in A. veronii strains isolated from freshwater fish (p = 0.0125) and domestic animals (p < 0.0001). B Comparison of the A. veronii genomes with T3SS (representative strain A29V) and without T3SS (representative strain FC951) shows that the AVI-1 genomic island is located adjacent to a gene encoding crossover junction endodeoxyribonuclease (red). The identical proteins in these two strains are shaded in grey. C Genes in the AVI-1 genomic island that encodes T3SS components. *Indicates statistical significance (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001). Other human samples include A. veronii strains isolated from sputum, wound infection, cholangiolithiasis bile and fecal samples of individuals without clinical information. Other animals include A. veronii strains isolated from mosquito gut, insect gut, Hirudo verbena digestive tract, grass carp, Heterelmis comalensis, Xiphophorus helleri, frog, snail, Andrias advidianus and alligator. The food group included strains isolated from various food