BMC Genomics

Table 1 Candidate genes putatively selected by two statistical methods (F_ST and log₂ θπ ratio and) affecting heat stress and immune responses traits in indigenous chicken ecotypes

From: Genetic diversity and signatures of selection for heat tolerance and immune response in Iranian native chickens

Selected comparative model	Statistical-Method	Gene	Chr.*	Summary of gene function
Native ecotypes – White-Leghorn line	F_ST (top 5%)	HSPA9	13	Heat stress [39]
		AHSA1	5	Heat stress [40]
		HSPH1	1	Heat stress [41, 42]
		DNAJC10	7	Heat stress [43]
		DNAJC6	8	Heat stress [44]
		DNAJC15	1	Heat stress [43]
		DNAJC5G	3	Heat stress [43]
		DNAJA4	10	Heat stress [43]
		IL3	13	Immune response [45, 46]
		IL13	13	Immune response [45, 46]
		IRF1	13	Immune response [47]
	log2(θπ·Native/θπ·Commercial) (top 1%)	HSP70	5	Heat stress [45, 48,49,50]
		HSPD1	7	Heat stress [39, 51]
		HSPH1	1	Heat stress [41, 42]
		NBEA	1	Heat stress [52]
		HSP90B1	1	Heat stress [39, 53]
		HSP90AB1	3	Heat stress [54]
		HSPA5	17	Heat stress [55]
		HSPB1	19	Heat stress [55]
		HSPA8	24	Heat stress [55]
		IRF1	13	Immune response [47]
		IL5	13	Immune response [45, 46]
		IL3	13	Immune response [45, 46]
		DNAJC15	1	Heat stress [43]
Native ecotypes- Arian line	F_ST (top 5%)	HSP90B1	1	Heat stress [39, 53]
		HSPH1	1	Heat stress [41, 42]
		DNAJC24	5	Heat stress [43]
		DNAJC6	8	Heat stress [44]
		IL5	13	Immune response [45, 46]
	log2(θπ·Native/θπ·Commercial) (top 1%)	HSPH1	1	Heat stress traits [41, 42]
		PLCB4	3	Immune response and heat stress [51, 56, 57]
		IRF1	13	Immune response [47]

^*Chromosome

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ISSN: 1471-2164

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