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Table 1 The readthrough rules derived from natural suppressor tRNAs for nonsense mutations

From: Frameshift and wild-type proteins are often highly similar because the genetic code and genomes were optimized for frameshift tolerance

Site

tRNA (AA)

Codon

supD

Ser (S)

UAG

supE

Gln (Q)

UAG

supF

Tyr (Y)

UAG

supG

Lys (K)

UAA

supU

Trp (W)

UGA

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BMC Genomics

ISSN: 1471-2164

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