Table 2 Top 10 sites most significantly associated with gestational age in the meta-analysis of START and CHILD
Site | Chr | Position | Gene | Estimate (CI) | Nominal P value | Adjusted P value |
|---|---|---|---|---|---|---|
cg11932158 | 3 | 155,422,129 | PLCH1 | -0.019 (-0.022, -0.016) | 4.8 × 10− 47 | 1.9 × 10− 41 |
cg18623216 | 3 | 155,421,970 | PLCH1 | -0.021 (-0.024, -0.018) | 3.7 × 10− 46 | 1.5 × 10− 40 |
cg16103712 | 8 | 99,023,869 | MATN2 | -0.023 (-0.026, -0.020) | 1.2 × 10− 45 | 4.8 × 10− 40 |
cg17133774 | 1 | 6,198,667 | CHD5 | -0.018 (-0.020, -0.015) | 4.1 × 10− 45 | 1.6 × 10− 39 |
cg12713583 | 19 | 940,724 | ARID3A | -0.022 (-0.025, -0.019) | 6.3 × 10− 45 | 2.5 × 10− 39 |
cg04347477 | 12 | 125,002,007 | NCOR2 | -0.019 (-0.022, -0.016) | 5.3 × 10− 41 | 2.1 × 10− 35 |
cg08817867 | 17 | 19,656,554 | - | -0.018 (-0.020, -0.015) | 5.4 × 10− 39 | 2.1 × 10− 33 |
cg02001279 | 19 | 940,967 | ARID3A | -0.013 (-0.015, -0.011) | 7.7 × 10− 39 | 3.0 × 10− 33 |
cg08412913 | 16 | 85,429,522 | - | -0.011 (-0.013, -0.010) | 1.3 × 10− 35 | 4.9 × 10− 30 |
cg06870470 | 19 | 11,315,767 | DOCK6 | -0.019 (-0.022, -0.016) | 8.2 × 10− 35 | 3.2 × 10− 29 |