Table 3 Replicated maternal smoking-associated sites in CHILD
Site | Chr | Position | Gene | Estimate (se) | Nominal P value | Adjusted P value | Literature Estimate (se) | Author (PMID) |
|---|---|---|---|---|---|---|---|---|
cg05549655 | 15 | 75,019,143 | CYP1A1 | 0.027 (0.006) | 3.8 × 10− 6 | 9.4 × 10− 5 | 0.019 (0.001) | Joubert et al. 27,040,690 |
cg11924019 | 15 | 75,019,283 | CYP1A1 | 0.043 (0.010) | 2.2 × 10− 5 | 5.6 × 10− 4 | 0.025 (0.002) | Joubert et al. 27,040,690 |
cg22549041 | 15 | 75,019,251 | CYP1A1 | 0.047 (0.011) | 3.5 × 10− 5 | 8.9 × 10− 4 | 0.066 (0.004) | Joubert et al. 27,040,690 |
cg23067299 | 5 | 323,907 | AHRR | 0.036 (0.008) | 4.7 × 10− 5 | 0.001 | 0.030 (0.002) | Joubert et al. 27,040,690 |
cg22132788 | 7 | 45,002,486 | MYO1G | 0.051 (0.013) | 7.9 × 10− 5 | 0.002 | 0.023 (0.001) | Joubert et al. 27,040,690 |
cg18092474 | 15 | 75,019,302 | CYP1A1 | 0.041 (0.010) | 1.2 × 10− 4 | 0.003 | 0.051 (0.003) | Joubert et al. 27,040,690 |
cg12803068 | 7 | 45,002,919 | MYO1G | 0.060 (0.016) | 2.8 × 10− 4 | 0.007 | 0.070 (0.003) | Joubert et al. 27,040,690 |
cg12101586 | 15 | 75,019,203 | CYP1A1 | 0.034 (0.009) | 4.1 × 10− 4 | 0.010 | 0.045 (0.003) | Joubert et al. 27,040,690 |