Fig. 7
Two cases of inverse GBM class-level shifts in transcription. A Transcriptional differences (log2 fold change) plotted against GBM level (% methylation). B Density plots of the log2 fold changes in transcription for the lowly methylated and highly methylated classes for Bumblebee (contrasting reproductive vs sterile individuals) and Honeybee (contrasting nurse vs forager subcastes). In these two cases, the lowly methylated class tended to be downregulated and the highly methylated class tended to be upregulated