Fig. 1
From: Deep learning for de-convolution of Smad2 versus Smad3 binding sites
Translocation of LAP-Smads from the cytoplasm to the nucleus upon stimulation with TGF β-1, shown via high content imaging in MDA-MB-231 cells. Left, LAP-Smad2, right LAP-Smad3. Cell nuclei were stained with red Hoechst stain (DAPI channel). Green GFP stain (FITC channel) showed predominantly cytoplasmic localization of LAP-Smads in the absence of TGF β-1 stimulation, and translocation to the nucleus after TGF β-1 stimulation