Table 1 Overview of existing scDNA-Seq simulators
From: SCSilicon: a tool for synthetic single-cell DNA sequencing data generation
Tool | Journal | Supported Variants | Other Facilities | |||
|---|---|---|---|---|---|---|
| Â | Â | SNV | Indel | CNV | Cell Cluster | Breakpoints |
CellCoal [19] | Mol. Biol. Evol. | \(\checkmark \) | - | - | - | - |
SCSsim [20] | Bioinformatics | \(\checkmark \) | \(\checkmark \) | \(\checkmark \) | - | - |
SCSIM [21] | BMC Bioinformatics | \(\checkmark \) | - | - | - | - |
SingleCellCNABenchmark [22] | PLoS Comput. Biol | - | - | \(\checkmark \) | - | - |
SCSilicon | - | \(\checkmark \) | \(\checkmark \) | \(\checkmark \) | \(\checkmark \) | \(\checkmark \) |