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Fig. 3 | BMC Genomics

Fig. 3

From: Gene expression profiling of RIP2-knockdown in HD11 macrophages — elucidation of potential pathways (gene network) when challenged with avian pathogenic E.coli (APEC)

Fig. 3

RNA-seq profiling in the comparisons of RIP2 knockdown HD11 macrophages group (shRIP2) vs. wild type cells group (WT) and RIP2 knockdown HD11 macrophages combined with APEC infection group (shRIP2 + APEC) vs. APEC infection group (APEC). A Heatmap analysis for the transcriptome data from the comparison of shRIP2 vs. WT. Red color indicate upregulation, while bule means downregulation. B The expression levels of differentially expressed genes (DEGs) in the comparison of shRIP2 vs. WT. Red spots represent DEGs for upregulation, blue spots for downregulation, and grey spots for unchanged genes in the comparison of shRIP2 vs. WT. C The distribution of the differentially expressed genes (DEGs) in the comparison of shRIP2 vs. WT. D Heatmap analysis for the transcriptome data from the comparison of shRIP2 + APEC vs. APEC. Red color indicate upregulation, while bule means downregulation. E The expression levels of the differentially expressed genes (DEGs) in the comparison of shRIP2 + APEC vs. APEC. Red spots represent DEGs for upregulation, blue spots for downregulation, and grey spots for unchanged genes in the contrast of shRIP2 + APEC vs. APEC. F The distribution of the differentially expressed genes (DEGs) in the comparison of shRIP2 + APEC vs. APEC

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