Fig. 2

A A picture of an OCA patient (Patient.13 in Table 1) with white skin color and white hair color. B A pedigree drawing of Sanger sequencing of the OCA patient. The girl inherited the c.1349C > T and c.1514 T > C from father and mother, respectively. C The p.F505 in OCA2 is highly conserved amino acids throughout evolution. D Modeling of the amino acids conformation changes by SWISS-MODEL