Fig. 8

ATAC-seq and RNA-seq log₂ fold changes do not predict insulin inducibility. A ATAC-seq and B) RNA-seq log₂ fold changes from S2 cells were correlated to insulin-induced luciferase activity, shown as the ratio between luciferase activity in vehicle- vs. insulin treated cells. C Correlation between the ATAC-seq peaks driving significantly increased luciferase activity and associated ATAC-seq log₂ fold changes. D Correlation between the ATAC-seq peaks driving significantly increased luciferase activity and RNA-seq log₂ fold changes in the associated genes. Associations were analyzed by Pearson correlation analysis. Each point represents a biological replicate, and each peak was tested in triplicate