Table 2 Examples of enriched gene ontologies and associated genes involved in neural plasticity and activity that were up-regulated (p ≤ 0.01) by ocean acidification in the olfactory rosette of F2 European Sea Bass (Dicentrarchus labrax) juveniles

Neuron projection

Axon guidance

15

apbb1, cdk5, epha5, epha8, ephb2, kif5c, gap43, sptbn4, tgfb2

Axon extension

3

cdk5, map1b, sema3a

Intracellular signalling transduction neuroplasticity

Neurotrophin TRK receptor sig. pathway

19

adcy6, arhgef7, calm1, erbb4, gab1, kras, ngef, shc1, vav2

Glutamate signalling pathway

13

gnaq, glur2b, gria1a, gria3b, gria4k, grik2, grik5, grin3a, grind2d

Ephrin signalling pathway

9

chn1, efna5, ek1, epha5, epha7, epha8, ephb1, ephb2, etk2

Regulation of synaptic plasticity

22

camk2b, cplx2, grik2, kcnn2, nf1, nptn, shank3, syngr1

Regulation of action potential

21

ank2, ank3, cacna1d, kcnip1, kcnc2, ryr2, scn1a, scn2b

Reg. of the neurotransmitter levels

34

cacna1a, gabra2, napb, nf1, rims1, slc6a13, snap25, stx1a, trpm7