Skip to main content

Table 2 Heart Significant Modules

From: Transcriptomic analysis provides insights into molecular mechanisms of thermal physiology

Module KEGG Pathway Module Size Hub MM MM Positive MM KEGG Terms in Pathway
ME1_heart MAPK signaling pathway* 194 SAC3D1 0.51 74.70% K04459
K20216
ME2_heart Endocytosis* 147 NCKAP5L 0.52 31.30% K12471
ME3_heart FoxO signaling pathway* 281 CLMPB 0.53 23.80% K11411
ME4_heart RNA degradation 168 TRAFD1 0.49 32.10% K03681
ME5_heart Metabolic pathways 336 LOC105935504 0.39 30.90% K00166
K00232
K03844
K05546
ME6_heart NA 554 WNT5B 0.65 34.10% NA
ME7_heart NA 454 MOSPD2 0.57 30.60% NA
ME8_heart Oxidative phosphorylation* 142 TXLNA 0.45 32.40% K0393
ME9_heart Ribosome* 90 YIF1B 0.54 66.70% K02899
  1. Columns include: Module = identifier for module eigengene (ME, first principal component of module), KEGG Pathway = top KEGG pathway determined by number of KEGG terms, Module Size = number of mRNAs in the module, Hub MM = mRNA with highest correlation with module eigengene, MM = correlation of hub mRNA with module eigengene, Positive MM = proportion of mRNAs with positive MM in the module, KEGG Terms in Pathway = enriched KEGG terms in the listed KEGG pathway.
  2. *Indicates modules where more than one KEGG Pathway had the same number of enriched KEGG terms, in which case the most informative KEGG pathway was selected