Transcriptomic analysis provides insights into molecular mechanisms of thermal physiology

BMC Genomics

Table 4 Brain Significant Modules

Module	KEGG Pathway	Module Size	Hub MM	MM	Positive MM	KEGG Terms in Pathway
ME1_brain	Metabolic pathways	393	IDH3B	0.47	26.40%	K00323
						K01443
						K10106
						K19006
ME2_brain	Tight junction	198	LOC105921153	0.52	28.20%	K07198
						K08018
						K08020
ME3_brain	Lysosome	342	LRCH3	0.58	25.10%	K01134
ME3_brain	Lysosome	342	LRCH3	0.58	25.10%	K08568
ME4_brain	RNA degradation*	142	SI:CH211-244C8.4	0.36	21.10%	K03681

Columns include: Module = identifier for module eigengene (ME, first principal component of module), KEGG Pathway = top KEGG pathway determined by number of KEGG terms, Module Size = number of mRNAs in the module, Hub MM = mRNA with highest correlation with module eigengene, MM = correlation of hub mRNA with module eigengene, Positive MM = proportion of mRNAs with positive MM in the module, KEGG Terms in Pathway = enriched KEGG terms in the listed KEGG pathway
*Indicates modules where more than one KEGG Pathway had the same number of enriched KEGG terms, in which case the most informative KEGG pathway was selected

ISSN: 1471-2164