Fig. 1

Phylogenesis of highly conserved neighbor gene families of the group XIV of CTLDcps. Phylogenetic reconstruction of forkhead-box, fos, ovo gene families of transcription factors. Nucleotide sequences were aligned and subjected to phylogenetic analysis using ML inference. Bootstrap is indicated at each node. Monophyletic subtype clusters, neighbor to a specific CTLDcp, are color-coded and specified in the figure. A Phylogenetic analysis of FOXA2 (Thrombomodulin-CD93 locus) and FOXA1 nucleotide sequences (Clec14A locus), ML inference was obtained using the TVMe + R3 evolutionary model. B Phylogenetic analysis of Ovo-like-2 (Thrombomodulin-CD93 locus) and Ovo-like-1 (CD248 locus) nucleotide sequences, ML inference was obtained using the SYM + R4 evolutionary model. C Phylogenetic analysis of Fos-like-1 (CD248 locus) and c-FOS (Clec14A locus) nucleotide sequences, ML inference was obtained using the TIM3e + R4 evolutionary model. Capital letters beside the species indicate duplicated genes lying on the same chromosome, while small letters indicate duplicated genes lying on different chromosomes