Fig. 4

Phylogenetic reconstruction of cyclostome and gnathostome CTLDcps. A Tree reconstruction was performed with representative species per class using ML statistic approach with WAG + R5 as evolutionary model. Numbers indicate bootstrap values. Protein clusters within the tree are color-coded. B Schematic trees representative two statistically significant alternative topologies. The tree on the left shows CTLDcp-γ as Clec14A ortholog, while the tree on the right inferred cyclostomes as monophyletic group and sister to Clec14A. Capital letters beside the species indicate duplicated genes lying on the same chromosome, while small letters indicate duplicated genes lying on different chromosomes