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Fig. 1 | BMC Genomics

Fig. 1

From: Comparative genomic analysis of the human genome and six bat genomes using unsupervised machine learning: Mb-level CpG and TFBS islands

Fig. 1

DegeDi-BLSOMs of bat and human genomes and the distribution of dinucleotides on their chromosomes. A BLSOM constructed for the DegeDi composition of 100-kb sequences in six bats. Nodes containing sequences from more than one species are indicated in black, and those containing sequences from a single species are indicated in color specific to the species: Rousettus aegyptiacus (Aeg) ( ), Phyllostomus discolor (Dis) ( ), Rhinolophus ferrumequinum (Fer) ( ), Pipistrellus kuhlii (Kuh) ( ), Molossus molossus (Mol) ( ) and Myotis myotis (Myo) ( ). The total number of nodes (grid points) was set to 1/20 of the total number of 100-kb sequences. Bi The BLSOM for the 100-kb DegeDi of three bats and humans was constructed and displayed as described in A. The colors representing the species are as follows: Aeg ( ), Fer ( ), Myo ( ) and Hum ( ). Bii Each grid point was colored according to the species with the highest value. Ci DegeDi-BLSOM for 1-Mb sequences with a 100-kb sliding step for three bats and humans. Each grid point is displayed as described in Bi. Cii Each grid point is displayed as described in Bii. Ciii U-matrix. D Heatmaps for the DegeDi-BLSOM described in Ci. E The occurrence frequency (%) of AC + GT and GA + TC in 1-Mb sliding windows with a 100-kb step is plotted on four human chromosomes. The central position of the primary constriction of each chromosome, as inferred from the UCSC Genome Brower (https://genome.ucsc.edu/), is indicated by the vertical magenta bar. F The occurrence frequency (%) of CG is plotted on four bat scaffolds

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