Fig. 4

Validation of ANXA2-regulated alternative splicing events in key genes of inflammation pathways. A RASEs in LITAF. B RASEs in UBA52. C RASEs in RBCK1. The altered ratio of alternative splicing (AS) events in RNA-seq was calculated using the formula: AS junction reads / (AS junction reads + Model junction reads); while the altered ratio of AS events in qRT-PCR was calculated using the formula: AS transcripts level / Model transcripts level. (n = 3, *P < 0.05,**P < 0.01, ***P < 0.001, calculated using the student’s t-test)