Fig. 2

Duplex Sequencing mutation frequencies by the mutagenesis panel target in the bone marrow of MutaMouse animals across BaP dose groups and controls (0 mg/kg/day). Data are represented as the average MF across animals for each individual target. Chromosome number for each DS mutagenesis panel target is shown on the x-axis, with intergenic (red font) and genic (black font) targets specified (chr1.2 denotes the 2nd target on chromosome 1). DS targets are ordered from highest to lowest MF at the high BaP dose (50 mg/kg/day). The red line indicates the fold-difference in MF between the highest MF and the lowest MF at the high dose. The green and blue lines indicate the fold-difference in MF between the highest MF and lowest MF at the high dose within intergenic and genic targets, respectively