Fig. 4

Prevalence of mutations found in this study during evolution of SARS-CoV-2. Schematic representation showing the prevalence of mutations found in genomes of SARS-CoV-2 obtained from COVID-19 patients. In the y axis is indicated a ratio used as a spreading indicator, which was estimated using the number of SARS-CoV-2 genomes in which each mutation was found, and the number of countries where these mutations were reported. Amino acid mutations are shown by vertical lines in different genome regions. Mutations identified in survivors are indicated with red circles, in non-survivors with black circles, and in both groups in green. The abbreviations of genes modified and respective amino acid changes are indicated above the nucleotide changes