Fig. 2
From: Exploring Lead loci shared between schizophrenia and Cardiometabolic traits
Pleiotropy analysis. a Plot of fold enrichment vs. nominal -log10 P for SCZ below the standard GWAS threshold of P value < 5 × 10− 8 as a function significant of the association with BMI. b Plot of fold enrichment versus nominal -log10 P values for BMI below the standard GWAS threshold of P value < 5 × 10− 8 as a function of significance of the association with SCZ. c Plot of fold enrichment vs. nominal -log10 P for SCZ below the standard GWAS threshold of P value < 5 × 10− 8 as a function of significance of the association with TG. d Plot of fold enrichment of TG versus nominal -log10 P values for below the standard GWAS threshold of P value < 5 × 10− 8 as a function of significance of the association with SCZ. e Local genetic correlation and local SNP-heritability between SCZ and BMI. f Local genetic correlation and local SNP-heritability between SCZ and TG. For each panel (e&f), the top section represents local genetic correlation, the middle section represents local genetic covariance, where significant local genetic correlation and covariance after multiple testing correction are highlighted in blue; and the bottom part represents local SNP-heritability for individual trait