Fig. 3

Common genetic variants jointly associated with SCZ and BMI (3a) and TG (3b) at conjunctional false discovery rate (conjFDR) less than 0.05. Manhattan plot showing the –log10 transformed conjFDR values for each SNP on the y-axis and chromosomal position along the x-axis. The dotted horizontal line represents the threshold chosen for reporting shared associations (−log (FDR) values of 1.3 corresponds to a cFDR ≤0.05). Independent lead single-nucleotide polymorphisms are highlighted with a black outline. The significant shared signal in the major histocompatibility complex region (chr6:25119106–33,854,733 and chr8:7242715–12,483,982) were deleted in the analysis. Further details are provided in Additional file 1 Supplementary Table 4 and Supplementary table 4_1