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Table 1 Functional annotations of genes from the histidine metabolism subsystem

From: Evolution of transcriptional regulation of histidine metabolism in Gram-positive bacteria

Name

Functional role

HisZ

ATP phosphoribosyltransferase (EC 2.4.2.17)

HisG

ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17)

HisD

Histidinol dehydrogenase (EC 1.1.1.23)

HisB

Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19)

HisH

Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-)

HisA

Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16)

HisF

Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)

HisI

Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19)

HisE

Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)

HisC

Histidinol-phosphate aminotransferase (EC 2.6.1.9)

HisJ

Histidinol-phosphatase (EC 3.1.3.15)

HisR

Histidine repressor, TrpR family

HisX

Histidine ABC transporter, histidine-binding protein

HisY

Histidine ABC transporter, permease protein

HisZ*

Histidine ABC transporter, ATP-binding protein

YuiF

Histidine permease YuiF

  1. The HisZ component of histidine ABC transporter is marked with asterisk to distinguish it from eponymous enzyme