Table 2 Distribution and functional content of HisR regulons in Firmicutes
From: Evolution of transcriptional regulation of histidine metabolism in Gram-positive bacteria
Order | Genera (examples) | Target genes | Count |
|---|---|---|---|
Bacillales (126 genomes) | Bacillus; Brevibacillus; Geobacillus; Paenibacillus; etc | his operon | 40 |
Bacillus; Brevibacillus; Paenibacillus; Solibacillus; Staphylococcus etc | his operon; yuiF | 52 | |
Desmospora; Kurthia; Lysinibacillus; Salinicoccus; etc | his operon; hisR | 26 | |
Lactobacillales (4 genomes) | Enterococcus, Carnobacterium | tdcP-tdcA-tyrT | 4 |
Eubacteriales (169 genomes) | Clostridium; Eubacterium; Ruminococcus; Subdoligranulum; etc | his operon | 22 |
Alkaliphilus; Clostridium | his operon; yuiF | 2 | |
Christensenella; Anaerostipes; Blautia; Butyrivibrio; Coprococcus; etc | his operon; hisR | 114 | |
Lachnobacterium; Lachnoclostridium; Bryantella; Roseburia; etc | his operon; hisXYZ* | 86 | |
Clostridium | yuiF | 3 | |
Clostridium; Eubacterium; Caloramator | hisXYZ* | 6 | |
Eubacterium; Blautia; Oribacterium; Peptococcus; Flavonifractor; etc | hisR; hisXYZ* | 8 | |
Halanaerobiales (7 genomes) | Halanaerobium; Halothermothrix | his operon | 2 |
Halanaerobium; Halobacteroides | his operon; yuiF | 3 | |
Acetohalobium | his operon; hisR | 1 | |
Orenia | his operon; hisXYZ* | 1 | |
Natranaerobiales | Natranaerobius (1 genome) | his operon; hisR | 1 |
Thermoanaero-bacterales (36 genomes) | Caldicellulosiruptor; Desulfovirgula; Moorella; Caldanaerovirga; etc | his operon | 29 |
Carboxydothermus; Thermoanaerobacter | his operon; hisR | 7 | |
Acidaminococcales (4 genomes) | Acidaminococcus | his operon; hisR | 2 |
Phascolarctobacterium; Succinispira | his operon; hisXYZ* | 2 | |
Selenomonadales (16 genomes) | Megamonas; Mitsuokella;Selenomonas; Anaeromusa; Thermosinus | his operon; hisXYZ*; hisR | 14 |
Pelosinus; Selenomonas | hisXYZ*; hisR | 2 | |
Veillonellales (11 genomes) | Dialister; Megasphaera; Veillonella | his operon; hisXYZ*; hisR | 8 |
Anaeroglobus; Megasphaera; Veillonella | his operon; hisXYZ* | 7 | |
Tissierellales (13 genomes) | Anaerococcus; Finegoldia; Parvimonas | hisR | 7 |
Gottschalkia | his operon | 1 | |
Peptoniphilus | yuiF | 5 | |
TOTAL number of operons controlled by HisR (387 genomes): | Â | 635 | |