Fig. 1
From: Mendelian randomization of circulating proteome identifies actionable targets in heart failure
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12864-022-08811-2/MediaObjects/12864_2022_8811_Fig1_HTML.png)
Identification of blood proteins potentially implicated in HF. Manhattan plot depicting blood proteins associated with heart failure (HF) in cis-MR analysis. The localization of the gene encoding the blood protein is represented on the x-axis, whereas the y-axis represents the -log10P value for the association in MR. Red and blue dashed lines are the Bonferroni and FDR 5% threshold values respectively. Red dots are genes positively associated with the development of HF, and green dots are genes negatively associated with the development of HF