Fig. 8

RNAi-induced downregulation of Cry receptor-related genes differentially altered the insect susceptibility to Cry1AcF toxin. A Percent pupation and adult emergence data of dsRNA-treated G. mellonella during 7 to 10 days after ingestion. Each bar with same letter is indicative of no significant difference between treatments (P > 0.01, Tukey’s HSD test, n = 30). B Percent mortality data of Cry1AcF force-fed larvae, which were pre-inoculated with dsRNAs corresponding to five Cry receptor-related genes and one gut repair gene. Post 24 h of dsRNA treatment, LD₅₀ (27 ng per larva) and LD₉₀ (90 ng per larva) doses of Cry1AcF were orally delivered. After another 24 h mortality data was recorded. Different letters are indicate significant difference between treatments (P < 0.01, Tukey’s HSD test, n = 50)