Fig. 6

The expressed TRAV and TRBV repertoire. Single cell analysis of lung mononuclear cells from cynomolgus macaques reveals their functionally expressed TRAV and TRBV repertoire. Each dot represents a different subject (n = 22). All samples are from uninvolved lung tissue (i.e., uninfected tissue as observed at autopsy). TRAVs were determined for 22 subjects with a median of 968 cells (interquartile range 496–1833). TRBVs were determined for 21 subjects, with a median of 855 cells (interquartile range 375–1587). The distribution of TRAV (A) and TRBV (B) V regions segments used by the T cells from each individual was calculated. The values within averaged. Red bar, median (left axis). The number of individuals expressing a given TRAV or TRBV gene was also calculated (right axis). *, pseudogene; °, pseudogene in some haplotypes