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Fig. 5 | BMC Genomics

Fig. 5

From: Transcriptomic profiles of muscular dystrophy with myositis (mdm) in extensor digitorum longus, psoas, and soleus muscles from mice

Fig. 5

Mitochondrial respiratory complex I and ribosomal protein synthesis associated genes are the putative drivers of the poor energy status of mdm muscles. Hub genes identified from the protein–protein interaction (PPI) network were generated for the differentially expressed genes in the turquoise module with gene significance > 0.8, and the module membership > 0.8. The PPI network was created using STRING database. Dark blue denotes highest connectivity, and yellow stands for the least connectivity in the selected hub genes. Colors are based on the connectivity scores calculated by MCODE application in Cytoscape

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