Table 3 Pathways significantly affected in the nCR patients
From: Early changes in gene expression profiles in AML patients during induction chemotherapy
Pathway | 24 h vs baseline | 48 h vs 24 h | 48 h vs baseline |
|---|---|---|---|
STAT3 Pathway | Activated | Activated | Activated |
Production of Nitric Oxide and Reactive Oxygen Species in Macrophages | Activated | Activated | Activated |
IL-6 Signaling | Activated | Activated | Activated |
Toll-like Receptor Signaling | Activated | Activated | Activated |
Cell Cycle: G2/M DNA Damage Checkpoint Regulation | Activated | – | Activated |
Salvage Pathways of Pyrimidine Ribonucleotides | – | Activated | Activated |