Fig. 4

Venn diagram of upregulated imprinted genes in the mature neuronal cells in the whole brain datasets of Zeisel, Hochgerner [31] and Ximerakis, Lipnick [29]. Imprinted genes listed which show significant upregulation (q ≤ 0.05 and Log2FC ≥ 1) in the cells. Although not identical, these were all mature neural lineage cells with over-representations in the enrichment analysis. Parental-bias is indicated by colour (MEG—red, PEG—blue). From the 119 imprinted genes in the gene list, only 88 were common to both analyses (i.e., successfully sequenced and passed gene quality control filters). 45 imprinted genes were upregulated in neurons in the MBA, and in Ximerakis, Lipnick [29], 33 imprinted genes were upregulated in neurons and 48 genes in neuroendocrine cells. Genes in common from the two analyses are presented in bold and totalled in each section of the Venn Diagram, while genes found upregulated in one analysis but not available in the other analysis are included in small font and the number indicated in brackets