Fig. 6

GO and KEGG pathway analyses of the DElncRNAs and DEmRNAs. Shown are the GO term (A, C) and KEGG pathway enrichment (B, D) analyses of the large turquoise (A, B) and small cyan (C, D) modules. In the GO term analyses, the numbers of genes and false discovery rate (FDR) values are displayed for the top 5 GO terms in biological process (BP; upper panel), cellular component (CC; middle panel), and molecular function (MF; bottom panel). The blue column is the count value indicating the number of genes enriched in the GO term, and the red line is the -log₁₀ (FDR) value. In the KEGG pathway enrichment analyses, each row represents an enriched function, and the size of the bubble represents the p-value (KOBAS, http://kobas.cbi.pku.edu.cn). The KOBAS algorithm divides the clusters according to the values computed for the enriched pathway, and the color of each bubble represents a different cluster