Fig. 8

a The Protein−Protein Interaction Network (PPI) of all DEPs. b The PPI of proteins that were involved in the regulation of proteolysis. c The PPI of proteins involved in the degradation of the extracellular matrix. Yellow color represents upregulation and blue represents downregulation in the atretic follicle. d Western blot analysis of normal and atretic follicles. From left to right, lanes 1–3 are the three repeats of atreated follicles, and lanes 4–6 are the three repeats of normal follicles. Complete gels are presented in Supplementary Fig. S3. e The relative protein expression level of MMP3 and MMP9