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Table 1 Interchromosomal translocations identified in HD3 cell line based on the analysis of Hi-C heatmaps

From: Hi-C analysis of genomic contacts revealed karyotype abnormalities in chicken HD3 cell line

Interacting chr1

start, ± 5000 bp

end, ± 5000 bp

Interacting chr2

Insertion site and approximate breakpoint position, ± 5000 bp

1

180,580,000

194,260,000*

2

q:149,470,000

4

0*

16,835,000

5

qter:59,820,000

4

18,835,000*

51,490,000

6

pter:500,000

4

0*

16,835,000

7

pter:0–6,310,000

4

51,505,000*

91,280,000

17

qter:10,950,000

4

188,350,000

51,490,000*

19

qter:9,965,000

5

0*

59,820,000

9

ter**

6

500,000

35,460,000

19

ter

7

0

6,310,000*

5

qter:59,820,000

7

6,145,000

36,905,000

27

ter

7

4,110,000

36,905,000

33

ter

12

0

19,945,000

21

ter

12

0

19,945,000

23

qter:5,785,000

13

500,000

18,400,000

28

ter

17

505,000*

10,950,000

28

ter

17

505,000

10,950,000

33

ter

18

0*

11,040,000

3

pter:0

21

0

325 000*

5

pter:5000

21

0

325 000

9

pter:515,000

21

0

6,860,000

23

ter

24

0

6,270,000

3

p:2,200,000

27

0

5,035,000

23

ter

28

0

1,140,000

12

ter

28

0

1,140,000

21

ter

28

0

1,140,000

23

ter

28

0

4,970,000

33

ter

  1. * – region orientation relative to acceptor chromosome breakpoint location
  2. ** – the breakpoint position on the termini of p- or q- chromosome arms could not be identified unambiguously on the basis of a interchromosomal gradient pattern on the Hi-C map, the insertion site is therefore marked as terminal region of the chromosome – ter