Fig. 3

Comparison of SV identified by analysis of SR and LR SV genomic sequence. (A) These Venn diagrams show the overlap of the SVs identified by our analysis of LR or SR sequence for the indicated 5 strains. (B) These Sankey diagrams indicate the number and type of SR-SVs that were confirmed after analysis of the LR sequence for each strain. Overall, the percentage of SR-SVs that were confirmed by the LR analysis are: 99.4% for DEL, 5% for DUP, and 61.3% for INV. Duplications > 10 kB are the major cause of the discordance between the SR and LR results. (C) These Venn diagrams show the overlap of the deletions identified in three inbred strains (BTBR, 129Sv1, and A/J) by our analysis of LR and SR genomic sequence, and with those in the MGP datasets. The number of deletions that were uniquely present in the LR, MGP and SR datasets are indicated in the red, blue, and green areas, respectively. Overall, the LR datasets contain most of deletions found in the SR or MGP datasets, but the LR datasets contain many more deletions than were present in either the SR or MGP datasets