Table 2 Top down-regulated genes in rumen of treated vs control dairy buffaloes identified using EdgeR tool (nominal p-values < 0.05). (FC: fold change)

LOC112585166

serum amyloid A protein-like

−5.75

4.68

2.10E-05

LRP2

LOW QUALITY PROTEIN: low-density lipoprotein receptor-elated protein 2

−3.13

1.93

1.17E-02

NYAP2

neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 isoform X1

−2.04

2.04

9.19E-03

LOC102389855

cytochrome c oxidase subunit 7C, mitochondrial

−1.88

1.44

3.63E-02

MUC15

mucin-15

−1.76

1.55

2.80E-02

LOC102399021

cytochrome P450 1A1

−1.71

2.33

4.67E-03

LEF1

lymphoid enhancer-binding factor 1 isoform X5

−1.65

1.60

2.54E-02

TTPA

alpha-tocopherol transfer protein

−1.56

1.38

4.20E-02

LOC102399215

nuclear distribution protein nudE homolog 1-like

−1.5

1.46

3.48E-02

ZNF618

zinc finger protein 618 isoform X21

−1.27

2.15

7.15E-03

ROR2

tyrosine-protein kinase transmembrane receptor ROR2

−1.25

2.23

5.89E-03

CADPS

calcium-dependent secretion activator 1 isoform X17

−1.2

1.90

1.27E-02

SMOC2

LOW QUALITY PROTEIN: SPARC-related modular calcium-binding protein 2

−1.2

1.41

3.91E-02

LOC102400888

olfactory receptor 51E1 isoform X2

−1.19

1.55

2.80E-02

IZUMO1

izumo sperm-egg fusion protein 1 isoform X5

−1.16

1.47

3.41E-02

HSPA12A

heat shock 70 kDa protein 12A isoform X2

−1.13

1.68

2.09E-02

PODN

podocan

−1.09

1.73

1.85E-02

LOC112578513

multidrug resistance-associated protein 4-like

−1.08

1.83

1.47E-02

SYNPO2

synaptopodin-2 isoform X2

−0.99

1.34

4.61E-02

SMARCA1

probable global transcription activator SNF2L1 isoform X3

−0.96

1.63

2.34E-02