Table 1 Top five results for significantly enriched genes within each β-cell subpopulation, including gene ontology terms
Gene Set | Description | Ratio | FDR |
|---|---|---|---|
Beta 1 | |||
GO:0023061 | signal release | 4.60 | 6.89E-13 |
GO:0009914 | hormone transport | 4.72 | 3.23E-09 |
GO:0030133 | transport vesicle | 3.90 | 3.45E-07 |
GO:0019932 | s-messenger-mediated signaling | 4.34 | 3.45E-07 |
GO:0033500 | carbohydrate homeostasis | 3.89 | 4.43E-05 |
Beta 2 | |||
GO:0070482 | response to oxygen levels | 5.49 | 7.22E-08 |
GO:0006090 | pyruvate metabolic process | 10.55 | 6.13E-07 |
GO:0046939 | nucleotide phosphorylation | 10.45 | 2.33E-06 |
GO:0009132 | nucleoside diphosphate metabolic process | 8.84 | 2.55E-06 |
GO:0006091 | generation of precursor metabolites and energy | 4.53 | 3.34E-06 |
Beta 3 | |||
GO:0016327 | apicolateral plasma membrane | 31.35 | 0.004258 |
GO:0003735 | structural constituent of ribosome | 7.90 | 0.004258 |
GO:0005840 | ribosome | 5.42 | 0.02957 |
GO:0044445 | cytosolic part | 5.42 | 0.02957 |
GO:0031012 | extracellular matrix | 4.66 | 0.02957 |
Beta 4 | |||
GO:0043620 | regulation of DNA-templated transcription in response to stress | 37.35 | 0.000216 |
GO:0045926 | negative regulation of growth | 12.11 | 0.004441 |
GO:0035966 | response to topologically incorrect protein | 16.41 | 0.004441 |
GO:0042594 | response to starvation | 11.63 | 0.017622 |
GO:1,901,654 | response to ketone | 11.33 | 0.094767 |