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Fig. 2 | BMC Genomics

Fig. 2

From: Potential key genes involved in metabolic resistance to malathion in the southern house mosquito, Culex quinquefasciatus, and functional validation of CYP325BC1 and CYP9M12 as candidate genes using RNA interference

Fig. 2

The ShinyGO Pathway Analysis is used to illustrate the top 20 pathways in the comparison performed. All differentially expressed genes (DEGs) with a significant level (FDR value for DEG less than 0.05) are mapped to the referential canonical pathways available in the Culex quinquefasciatus database. The size of a circle represents the number of DEGs classified into one specific pathway category. Fold Enrichment (FE) indicates the percentage of DEGs belonging to a pathway, divided by the corresponding percentage in the background. FDR for FE demonstrates how likely the enrichment is by chance. (A) ShinyGO pathway analysis for the top 20 pathways in which the most DEGs (FDR for DEG with a cutoff value of 0.05) in the comparison between Cx. quinquefasciatus WI and CO groups were involved. (B) ShinyGO pathway analysis for the top 20 pathways in which the most DEGs (FDR for DEG with a cutoff value of 0.05) in the comparison between Cx. quinquefasciatus MR and MS groups were involved

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