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Fig. 6 | BMC Genomics

Fig. 6

From: Splicing complexity as a pivotal feature of alternative exons in mammalian species

Fig. 6

Splicing complexity changes during development. A hierarchical clustering for splicing complexity for events that have confident change (at least 20 supported reads) in splicing entropy larger than 0.5 and expression level of located gene larger than 10 TPM. Red arrow represents events that have stable and high splicing entropy during development. B 2D kernel density plots showing the largest change in splicing entropy (y-axis) and Ψ (x-axis). C the number of events that change in splicing entropy. Dev-events: events with largest splicing entropy ≥ 0.5 during development, non-Dev-events: events with largest splicing entropy < 0.5. D The relative ratio of events with splicing entropy changes larger than 0.5 among events that are not regulated in Ψ (max Δ Ψ < 0.1). E the distribution of splicing entropy changes for events in the humangain’ group

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