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Fig. 2 | BMC Genomics

Fig. 2

From: Intercellular crosstalk in adult dental pulp is mediated by heparin-binding growth factors Pleiotrophin and Midkine

Fig. 2

Dental pulp fibroblasts versus those from reference tissues. (a) PTN and MDK are differentially expressed genes in DP fibroblast versus reference tissue fibroblasts. (b) Gene ontology enrichment analysis using the DE genes from a identified significantly upregulated Biological Processes in DP fibroblasts. (c) Violin plots of PTN (upper) and MDK (lower) expression levels in fibroblasts of all tissues. (d) Dot plot showing percentage and average expression of PTN and MDK of fibroblasts of all tissues. (e) UMAP visualization of fibroblasts from all tissues integrated and colored by tissue of origin. (f) Unbiased classification identifying 9 clusters of fibroblast sup-populations. (g) Bar plot of the fraction of cells that compose each cluster shown in f, colored by tissue of origin. (h) Expression of PTN (upper) and MDK (lower) projected onto the UMAP plot of integrated fibroblasts. (i) Dot plot showing percentage and average expression of PTN and MDK by clusters of fibroblasts in f

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