Fig. 6

Sequence alignment of 42 CYP51 family members from different biological kingdoms [bacteria (1–4), plants (5–10), fungi (11, 13–31) and animals (12, 32–42)] in CYP51 substrate recognition sites (SRS) 1 and 4; 100% and more than 95% conserved residues are shaded in black and grey, respectively. Phyla-specific residues are highlighted in red or shaded in yellow. The accession number of sequences can be found in Supplemental data file 1