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Fig. 4 | BMC Genomics

Fig. 4

From: Restoration of aberrant gene expression of monocytes in systemic lupus erythematosus via a combined transcriptome-reversal and network-based drug repurposing strategy

Fig. 4

Interaction network showing the transcription factors that regulate the expression of the monocyte gene signature in SLE and the compounds that interfere with their function. Only nodes with degree > 2 were demonstrated. The proteasome inhibitor “bortezomib” as well as several natural products emerged as potential drug candidates

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