Fig. 3

Genes associated with cardiac IREs are functionally different between zebrafish and mice. A Left, scatter plot comparing enrichment of biological process GO terms (-log10 transformed q-value) between zebrafish (x-axis) and mice (y-axis). Red dotted lines correspond to a q-value of 0.05. Right, donut plot showing the counts and percentages of different types of GO terms relative to zebrafish or mice (orange: only enriched in zebrafish, blue: only enriched in mice, red: enriched in both zebrafish and mice, grey: enriched in neither zebrafish nor mice). B Left, scatter plot showing enrichment of KEGG pathways (-log10 transformed q-value) between zebrafish (x-axis) and mice (y-axis). Red dotted lines stand for a q-value of 0.05. Right, donut plot displaying the counts and percentages of different types of KEGG pathways relative to zebrafish or mice as shown in (A). C, D Top 10 enriched GO terms (C) or KEGG pathways (D) in zebrafish and corresponding q-values (-log10 transformed) in mice. Red dotted lines stand for a q-value of 0.05. E, F Bar plots of top 10 enriched GO terms (E) or KEGG pathways (F) in mice and corresponding q-values (-log10 transformed) in zebrafish. Red dotted lines represent a q-value of 0.05