Fig. 5

Regional differences and characteristics of differentially enriched peaks between alpha, beta, and delta cells. A Distribution of regional preference across the annotated genome of differentially enriched peaks between alpha and beta cells. B Regional preference breakdown of differentially enriched peaks between alpha and beta cells, indicating prevalence of enrichment for each cell type and genomic annotation. Differentially enriched chromatin favored promoter-proximal peaks in alpha cells, and distal-intergenic regions in beta cells. C Distribution of regional preference across the annotated genome of differentially enriched peaks between alpha and delta cells. D Regional preference breakdown of differentially enriched peaks between alpha and delta cells, indicating prevalence of enrichment for each cell type and genomic annotation. Differentially enriched chromatin favored promoter-proximal peaks in alpha cells, and distal-intergenic regions in delta cells. E Distribution of regional preference across the annotated genome of differentially enriched peaks between beta and delta cells. F Regional preference breakdown of differentially enriched peaks between beta and delta cells, indicating prevalence of enrichment for each cell type and genomic annotation. Differentially enriched chromatin favored promoter-proximal peaks in delta cells, and distal-intergenic regions in beta cells