Fig. 4

Estimation error of the fitness effects and the establishment times. Comparison of the estimation error, measured between simulation and inference, for FitMut1 and FitMut2. A shows fitness effects and B shows establishment times. Each column corresponds to an average number of reads per lineage r. Different rows correspond to different classes DFEs: exponential and uniform. Each panel includes the inference error of two simulations (Methods section) from the same family of \(\mu (s)\) with different variances (blue for smaller variance, red for larger variance). Each dot in the scatter plot represents an adaptive mutation that established in the simulation and was identified by both FitMut2 and FitMut1. Dots falling within the gray region indicate the adaptive mutations that were more accurately inferred with FitMut2 than with FitMut1. Blue and red dots are colored by their occurrence time \(t^*\) for (A), and by their true fitness \(s^*\) for (B). \(\mu (s)\) is plotted in the 5th column (blue for small variance, red for large variance)