Systematically identifying genetic signatures including novel SNP-clusters, nonsense variants, frame-shift INDELs, and long STR expansions that potentially link to unknown phenotypes existing in dog breeds

Table 3 Breed-specific INDELs within coding regions

Breed	Chromosome	Position	Genomic region	Variant type	Reference allele	Alternative allele	Position of the first impacted amino acid on protein
NorwichTerrier	chr5	82436555	ZDHHC1	frameshift variant	CG	C	156/511
Chow Chow	chr8	45457109	SIPA1L1	disruptive inframe deletion	AGTC	A	1641/1806
Bernese Moutain Dog	chr16	48047125	CENPU	conservative inframe deletion	TGAA	T	84/422
Airedale Terrier	chr18	40255586	OR5J2	frameshift variant	AG	A	297/312

ISSN: 1471-2164