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Fig. 5 | BMC Genomics

Fig. 5

From: Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons

Fig. 5

Validation of gene ontology and comparison to bulk-RNA-seq from ex vivo DA neurons. A A bar chart showing normalized bulk RNA-seq read counts from genes upregulated at 39 °C that overlap the “immature neurons” predicted cell type. B A bar chart showing normalized bulk RNA-seq read counts from genes upregulated at 39 °C that overlap the “oligodendrocyte” predicted cell type. C A bar chart showing normalized bulk RNA-seq read counts from genes downregulated at 39 °C that overlap the “pluripotent stem cell” predicted cell type. D A Pearson correlation heatmap comparing the transcriptomes of SN4741 cells at 37 °C and 39 °C to midbrain (MB) or forebrain (FB) embryonic mouse dopaminergic neurons. (NS = Not significant, * = p < 0.05, ** = p < 0.01, *** = p < 0.001, **** = p < 0.0001)

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BMC Genomics

ISSN: 1471-2164

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