Fig. 3

Selective sweep analysis of the rabbit genome. a Identification of genomic regions with strong selective sweep signals in Angora rabbits. Distribution of Angora ZHp values (ZHp_A) and ZFst values of Angora vs. New Zealand and Rex (ZFst_A-RN), which were calculated in 100 kb windows sliding in 10 kb steps. Data points located to the right of the vertical dotted lines (corresponding to 5% right tails of the empirical ZFst distribution) and below the horizontal dotted line (5% right tail of the empirical ZHp distribution) are identified as selected regions (red points). b KEGG enrichment analysis for the identified candidate genes. The top 10 enrichment pathways are presented. c Manhattan plot of selective sweeps in Angora rabbits. The chromosome numbers are presented along the x-axes. Bins of ZFst and ZHp are presented along the y-axes. The Manhattan plots are pointed the value for each window of ZFst and ZHp. The horizontal dashed lines indicate the threshold at ZFst = 1.967 and ZHp = -1.825. Genes residing within the selected regions and associated with hair growth are indicated by their gene names