Fig. 8

Model construction and validation. (A, B) MI and IS characteristic gene change curves; y-axis (above) is remaining number of variable genes whose variable coefficient is not zero at current logarithm of lambda. (C, D) MI and IS cross-check lambda results; there are two dashed lines in plot: one is minimum mean squared error and other is standard error of minimum mean squared error. (E, F) Box plot of differences in gene expression between MI and IS for IL1B, FOS, JUN, FCGR2A, IL6, AKT1, DRD4, GLUD2, and SRC; *p < 0.05; **p < 0.01; ***p < 0.001 (G, H) ROC curves for IL1B, FOS, JUN, FCGR2A, IL6, AKT1, DRD4, GLUD2, and SRC genes in MI and IS. IS: ischemic stroke; MI: myocardial ischemia